Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL

Catalog number BNC880252-100

Price for BNC880252-100

Size / count 1x 100 µL

About this product

This MAb recognizes the 56. 5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e. g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC880252-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: K1B; KRT1B; Keratin; type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT77
Gene ID: 374454
NCBI Gene ID: 334989
UniProt: Q7Z794
Swiss Prot: Q7Z794
Host: Mouse
Species Reactivity: Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat, Turtle
Reactivity: Cytokeratin, Acidic
Immunogen: Human epidermal keratin
Target Antigen: Cytokeratin, Acidic
Clonality: Monoclonal
Clone: AE-1
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Cancer, Cytoskeleton
Positive Control: Skin or squamous cell carcinoma (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40-56.5 kDa
References & Citations: Woodock-Mitchell J et. al. Journal of Cell Biology 1982;95:580-8. |Tseng SCG et. al. Cell 1982; 30361
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL is BNC880252-100.

What sizes are available for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL?

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL in stock?

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL?

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF488A conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.