Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL

Catalog number BNC060315-100

Price for BNC060315-100

Size / count 1x 100 µL

About this product

This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan's strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2) . Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC060315-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Heparan sulfate proteoglycan of basement membrane; HSPG; Hspg2; LG3 peptide; Perlecan; PLC; SJS1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: HSPG2
Gene ID: 3339
NCBI Gene ID: 562227
UniProt: P98160
Swiss Prot: P98160
Host: Rat
Species Reactivity: Cow, Fish, Human, Monkey, Mouse, Pig
Reactivity: Heparan Sulfate Proteoglycan
Immunogen: Murine EHS laminin preparation
Target Antigen: Heparan Sulfate Proteoglycan
Clonality: Monoclonal
Clone: A7L6
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: Breast carcinomas, squamous cell carcinomas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: >400 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405L

Frequently Asked Questions

What is the catalog number for Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL?

The catalog number for Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL is BNC060315-100.

What sizes are available for Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL in stock?

Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL?

Estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL?

The safety data sheet for Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100bfd/msds/bnc060315-100.pdf.

What is Heparan Sulphate Proteoglycan (A7L6), CF405L conjugate, 0.1mg/mL used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.