CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL

Catalog number BNC470479-100

Price for BNC470479-100

Size / count 1x 100 µL

About this product

This MAb binds most strongly to the IIa isoforms of CD32 (FcRII), a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i. e. , IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470479-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD32A; Fc fragment of IgG low affinity IIa receptor; Fc gamma RIIa; FCGR2A; FcgRII; IGFR2; IgG Fc receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-a; Ly-17; Ly-m20; LyM-1; Lymphocyte antigen 17
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FCGR2A
Gene ID: 2212
NCBI Gene ID: 352642
UniProt: P12318
Swiss Prot: P12318
Host: Mouse
Species Reactivity: Human
Reactivity: CD32|Fc Gamma RIIa
Immunogen: Recombinant human FCGR2A protein
Target Antigen: CD32 | Fc Gamma RIIa
Clonality: Monoclonal
Clone: FCGR2A/479
Type: Primary
Source: Animal
Origin: Animal
Positive Control: K-562 cells. Lymph node, tonsil and placenta.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL?

The catalog number for CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL is BNC470479-100.

What sizes are available for CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL?

CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL in stock?

CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL?

CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a6061270361e105f47/msds/bnc470479-100.pdf.

What is CD32 (Fc Gamma RIIa) (FCGR2A/479), CF647 conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.