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Product details
Catalog number BNC040489-500
Price for BNC040489-500
Size / count 1x 500 µL
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF405S conjugate, 0.1mg/mL is BNC040489-500.
Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101e33/msds/bnc040489-500.pdf.
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous antican
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.
