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Product details
Catalog number BNC400489-100
Price for BNC400489-100
Size / count 1x 100 µL
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF640R conjugate, 0.1mg/mL is BNC400489-100.
Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous antican
Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.
