Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL

Catalog number BNC680489-100

Price for BNC680489-100

Size / count 1x 100 µL

About this product

DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC680489-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA topoisomerase I; TOP1MT; Topoisomerase I mitochondrial; Type IB Topoisomerase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TOP1MT
Gene ID: 116447
NCBI Gene ID: 528574
UniProt: Q969P6
Swiss Prot: Q969P6
Host: Mouse
Species Reactivity: Human
Reactivity: Topoisomerase I, Mitochondrial
Immunogen: Recombinant full-length human TOP1MT protein
Target Antigen: Topoisomerase I, Mitochondrial
Clonality: Monoclonal
Clone: TOP1MT/568
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A431 cells. Heart, Skeletal muscle, brain or fetal liver.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL?

The catalog number for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL is BNC680489-100.

What sizes are available for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL?

Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL in stock?

Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL?

Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e103054/msds/bnc680489-100.pdf.

What is Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (TOP1MT/568), CF568 conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.