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Product details

VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL

Catalog number BNUM0531-50

Price for BNUM0531-50

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Size / count 1x 50 µL

About this product

This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0531-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD309; Fetal liver kinase 1 (FLK-1) ; KDR; Kinase insert domain receptor (a type III receptor tyrosine kinase) ; KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Vascular endothelial growth factor receptor 2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
Kdr (Mouse)
Gene ID
16542
NCBI Gene ID
285
UniProt
35918
Swiss Prot
35918
Host
Rat
Species Reactivity
Mouse
Reactivity
CD309|Flk-1|KDR3|VEGF-R2
Immunogen
Recombinant full-length Mouse VEGFR2 protein
Target Antigen
CD309 | Flk-1 | KDR3 | VEGF-R2
Clonality
Monoclonal
Clone
DC101
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IHC, frozen (published)
Positive Control
Mouse epidermoid, renal cell carcinoma, pancreatic or glioblastoma cells.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
180-190 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Cancer Metastasis Rev (1998) 17(2):155-61. (functional studies) J Exp Med (2001) 193(9): 1005-1014. (Flow) FASEB J (2005) 19(14): 2005-2007. (IHC, frozen)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL?

The catalog number for VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL is BNUM0531-50.

What sizes are available for VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL?

VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL is available in the following size(s): 1x 50 µL.

Is VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL in stock?

VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL?

VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL?

Estimated delivery time for VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL?

The safety data sheet for VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is VEGF-R2 / CD309 / Flk-1 / KDR3 (DC101), 1mg/mL used for?

This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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