MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL

Catalog number BNC470612-500

Price for BNC470612-500

Size / count 1x 500 µL

About this product

This MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15. 3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i. e. treatment with Neuraminidase. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470612-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MUC1
Gene ID: 4582
NCBI Gene ID: 89603
UniProt: P15941
Swiss Prot: P15941
Host: Mouse
Species Reactivity: Human
Reactivity: CA15-3|CD227|EMA|MUC1
Immunogen: Human milk-fat globule membranes (HMFGM)
Target Antigen: CA15-3 | CD227 | EMA | MUC1
Clonality: Monoclonal
Clone: 115D8
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Mucins
Positive Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 265-400 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL?

The catalog number for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL is BNC470612-500.

What sizes are available for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL in stock?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL?

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a8061270361e106705/msds/bnc470612-500.pdf.

What is MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (115D8), CF647 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.