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Product details

Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1083-100

Price for BNCB1083-100

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Size / count 1x 100 µL

About this product

Recognizes a 34 kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor) . Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2) . It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1083-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cdc2; CDC28A; CDK1; CDKN1; CELL CYCLE CONTROLLER CDC2; Cell division control protein 2 homolog; Cell division cycle 2 G1 to S and G2 to M; Cell division protein kinase 1; Cyclin-dependent kinase 1; p34 Protein Kinase; P34CDC2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CDC2
Gene ID
983
NCBI Gene ID
334562
UniProt
P06493
Swiss Prot
P06493
Host
Mouse
Species Reactivity
Chicken, Guinea pig, Human, Mouse, Rat, Woodchuck, Xenopus
Reactivity
Cdk1|p34cdc2 Serine-Threonine Kinase
Immunogen
C-Terminal 2/3rds of Xenopus cdc2 expressed in E.coli
Target Antigen
Cdk1 | p34cdc2 Serine-Threonine Kinase
Clonality
Monoclonal
Clone
A17.1.1
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
HeLa cells. Human tonsil (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
34 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL?

The catalog number for Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL is BNCB1083-100.

What sizes are available for Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL?

Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL in stock?

Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL?

Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cdk1 / p34cdc2 Serine-Threonine Kinase (A17.1.1), Biotin conjugate, 0.1mg/mL used for?

Recognizes a 34 kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor) . Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2) . It shows no cross reaction with cdk2 p32. It supports the kinase ac

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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