Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL

Catalog number BNC881274-100

Price for BNC881274-100

Size / count 1x 100 µL

About this product

This MAb recognizes a protein of 56. 5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881274-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT10
Gene ID: 3858
NCBI Gene ID: 99936
UniProt: P13645
Swiss Prot: P13645
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: Cytokeratin 10
Immunogen: Human cytokeratin 10
Target Antigen: Cytokeratin 10
Clonality: Monoclonal
Clone: AE20
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: A431, HeLa, MCF7 cells. Esophagus or tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 56.5 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL is BNC881274-100.

What sizes are available for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL?

Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL in stock?

Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL?

Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF488A conjugate, 0.1mg/mL used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.