Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL

Catalog number BNC941274-100

Price for BNC941274-100

Size / count 1x 100 µL

About this product

This MAb recognizes a protein of 56. 5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941274-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT10
Gene ID: 3858
NCBI Gene ID: 99936
UniProt: P13645
Swiss Prot: P13645
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: Cytokeratin 10
Immunogen: Human cytokeratin 10
Target Antigen: Cytokeratin 10
Clonality: Monoclonal
Clone: AE20
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: A431, HeLa, MCF7 cells. Esophagus or tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 56.5 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL is BNC941274-100.

What sizes are available for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL?

Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL in stock?

Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL?

Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF594 conjugate, 0.1mg/mL used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.