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Product details

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1317-100

Price for BNCB1317-100

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Size / count 1x 100 µL

About this product

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3) . TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1317-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CHNG4; Thyroid stimulating hormone beta subunit; Thyroid stimulating hormone; beta precursor; Thyrotropin beta subunit; TSHB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TSHB
Gene ID
7252
NCBI Gene ID
406687
UniProt
P01222
Swiss Prot
P01222
Host
Mouse
Species Reactivity
Human
Reactivity
Thyroid Stimulating Hormone, beta
Immunogen
Recombinant human TSH beta fragment
Target Antigen
Thyroid Stimulating Hormone, beta
Clonality
Monoclonal
Clone
TSHb/1317
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Normal pituitary or its tumor.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
16 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL?

The catalog number for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL is BNCB1317-100.

What sizes are available for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL?

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL in stock?

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL?

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), Biotin conjugate, 0.1mg/mL used for?

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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