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Product details

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL

Catalog number BNUM1317-50

Price for BNUM1317-50

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Size / count 1x 50 µL

About this product

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3) . TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM1317-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CHNG4; Thyroid stimulating hormone beta subunit; Thyroid stimulating hormone; beta precursor; Thyrotropin beta subunit; TSHB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TSHB
Gene ID
7252
NCBI Gene ID
406687
UniProt
P01222
Swiss Prot
P01222
Host
Mouse
Species Reactivity
Human
Reactivity
Thyroid Stimulating Hormone, beta
Immunogen
Recombinant human TSH beta fragment
Target Antigen
Thyroid Stimulating Hormone, beta
Clonality
Monoclonal
Clone
TSHb/1317
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Normal pituitary or its tumor.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
16 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL?

The catalog number for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL is BNUM1317-50.

What sizes are available for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL?

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL in stock?

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL?

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL?

Estimated delivery time for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL?

The safety data sheet for Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) (TSHb/1317), 1mg/mL used for?

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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