P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL

Catalog number BNC041423-100

Price for BNC041423-100

Size / count 1x 100 µL

About this product

P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S) . p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041423-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Amplified in squamous cell carcinoma (AIS) ; Chronic ulcerative stomatitis protein (CUSP) ; EEC3; Keratinocyte transcription factor KET; LMS; NBP; p40; P51/P63; p53 like transcription factor; p53-related protein p63; RHS; SHFM4; TAp63alpha; TP53CP; TP53L; TP63; TP73; TP73L; Transformation-related protein 63; Trp53rp1; Trp6; 3; Tumor protein 63; Tumor protein p53-like; tumor protein p73-like
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TP63
Gene ID: 8626
NCBI Gene ID: 137569
UniProt: Q9H3D4
Swiss Prot: Q9H3D4
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Reactivity: P63
Immunogen: Recombinant human p63 protein fragment
Target Antigen: p63
Clonality: Monoclonal
Clone: TP63/1423R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HEK293 cells. Prostate Carcinoma or Lung or bladder squamous cell carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 63 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL?

The catalog number for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL is BNC041423-100.

What sizes are available for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL?

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL in stock?

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL?

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/1423R), CF405S conjugate, 0.1mg/mL used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.