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Product details

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1474-500

Price for BNCB1474-500

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Size / count 1x 500 µL

About this product

ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1474-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Transcriptional regulator ATRX; ATP-dependent helicase ATRX; RAD54 Homolog; X-linked helicase II; X-linked nuclear protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ATRX
Gene ID
546
NCBI Gene ID
533526; 653797
UniProt
P46100
Swiss Prot
P46100
Host
Mouse
Species Reactivity
Human
Reactivity
ATRX
Immunogen
Recombinant human ATRX protein
Target Antigen
ATRX
Clonality
Monoclonal
Clone
23c
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Raji, HeLa or A431 Cells. Pancreas, Adrenal, Ovary, Kidney, Prostate or Stomach.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
280 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL?

The catalog number for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL is BNCB1474-500.

What sizes are available for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL?

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL in stock?

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL?

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL?

The safety data sheet for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (23c), Biotin conjugate, 0.1mg/mL used for?

ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the ce

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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