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Product details

Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL

Catalog number BNC881530-100

Price for BNC881530-100

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Size / count 1x 100 µL

About this product

Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2 - dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881530-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Calpain 1; Calcium dependent protease small subunit 1; Calcium-activated neutral proteinase 1; Calpain 1 large subunit; Calpain mu-type; Calpain-1 catalytic subunit; CANP1; CANPL1; CAPN1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CAPN1
Gene ID
823
NCBI Gene ID
502842
UniProt
P07384
Swiss Prot
P07384
Host
Mouse
Species Reactivity
Human
Reactivity
Calpain 1
Immunogen
Recombinant full-length human CAPN1 protein
Target Antigen
Calpain 1
Clonality
Monoclonal
Clone
CAPN1/1530
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cytoskeleton
Positive Control
HeLa cells. Skin or Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~80 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL?

The catalog number for Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL is BNC881530-100.

What sizes are available for Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL?

Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL in stock?

Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL?

Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Calpain 1 (CAPN1/1530), CF488A conjugate, 0.1mg/mL used for?

Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2 - dependent processes including cell fusion, mitosis and meiosis. Calpains are

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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