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Product details

Calpain 1 (CAPN1/1530), 0.2mg/mL

Catalog number BNUB1530-500

Price for BNUB1530-500

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Size / count 1x 500 µL

About this product

Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2 - dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1530-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Calpain 1; Calcium dependent protease small subunit 1; Calcium-activated neutral proteinase 1; Calpain 1 large subunit; Calpain mu-type; Calpain-1 catalytic subunit; CANP1; CANPL1; CAPN1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CAPN1
Gene ID
823
NCBI Gene ID
502842
UniProt
P07384
Swiss Prot
P07384
Host
Mouse
Species Reactivity
Human
Reactivity
Calpain 1
Immunogen
Recombinant full-length human CAPN1 protein
Target Antigen
Calpain 1
Clonality
Monoclonal
Clone
CAPN1/1530
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cytoskeleton
Positive Control
HeLa cells. Skin or Tonsil.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
~80 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Calpain 1 (CAPN1/1530), 0.2mg/mL?

The catalog number for Calpain 1 (CAPN1/1530), 0.2mg/mL is BNUB1530-500.

What sizes are available for Calpain 1 (CAPN1/1530), 0.2mg/mL?

Calpain 1 (CAPN1/1530), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Calpain 1 (CAPN1/1530), 0.2mg/mL in stock?

Calpain 1 (CAPN1/1530), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calpain 1 (CAPN1/1530), 0.2mg/mL?

Calpain 1 (CAPN1/1530), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Calpain 1 (CAPN1/1530), 0.2mg/mL?

Estimated delivery time for Calpain 1 (CAPN1/1530), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Calpain 1 (CAPN1/1530), 0.2mg/mL?

The safety data sheet for Calpain 1 (CAPN1/1530), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1015ad/msds/bnub1530-500.pdf.

What is Calpain 1 (CAPN1/1530), 0.2mg/mL used for?

Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2 - dependent processes including cell fusion, mitosis and meiosis. Calpains are

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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