CD268 / BAFFR / TNFRSF13C (BAFFR/1557), CF405S conjugate, 0.1mg/mL

About this product

Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) ; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC041557-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

TNFRSF13C; BAFFR; BR3; BAFF receptor; BLyS receptor 3; CD268; CD268 antigen; CVID4; Prolixin; BAFF-R; BROMIX

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

TNFRSF13C

Gene ID

115650

NCBI Gene ID

344088

UniProt

Q96RJ3

Swiss Prot

Q96RJ3

Host

Mouse

Species Reactivity

Human

Reactivity

BAFFR|CD268|TNFRSF13C

Immunogen

Recombinant full-length human CD268 protein

Target Antigen

BAFFR | CD268 | TNFRSF13C

Clonality

Monoclonal

Clone

BAFFR/1557

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Positive Control

Raji cells. Tonsil and lymph node.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

19 kDa (Monomer) ; 40 kDa (Dimer)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF405S