SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL

Catalog number BNC681578-500

Price for BNC681578-500

Size / count 1x 500 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC681578-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ADD 1; bHLHd1; Class D basic helix-loop-helix protein 1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1c; SREBP-1; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1; Sterol regulatory element binding transcription factor 1; Sterol regulatory element-binding transcription factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SREBF1
Gene ID: 6720
NCBI Gene ID: 592123
UniProt: P36956
Swiss Prot: P36956
Host: Mouse
Species Reactivity: Human
Reactivity: SREBP1
Immunogen: Recombinant full-length human SREBF1 protein
Target Antigen: SREBP1
Clonality: Monoclonal
Clone: SREBP1/1578
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Ubiqutious expression in adult and fetal tissues.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 68/125 kDa mature/precursor
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL?

The catalog number for SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL is BNC681578-500.

What sizes are available for SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL in stock?

SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL?

The safety data sheet for SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a7061270361e106622/msds/bnc681578-500.pdf.

What is SREBP1 (SREBP1/1578), CF568 conjugate, 0.1mg/mL used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.