SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL

Catalog number BNC881578-500

Price for BNC881578-500

Size / count 1x 500 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881578-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ADD 1; bHLHd1; Class D basic helix-loop-helix protein 1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1c; SREBP-1; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1; Sterol regulatory element binding transcription factor 1; Sterol regulatory element-binding transcription factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SREBF1
Gene ID: 6720
NCBI Gene ID: 592123
UniProt: P36956
Swiss Prot: P36956
Host: Mouse
Species Reactivity: Human
Reactivity: SREBP1
Immunogen: Recombinant full-length human SREBF1 protein
Target Antigen: SREBP1
Clonality: Monoclonal
Clone: SREBP1/1578
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Ubiqutious expression in adult and fetal tissues.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 68/125 kDa mature/precursor
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL?

The catalog number for SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL is BNC881578-500.

What sizes are available for SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL in stock?

SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL?

The safety data sheet for SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101730/msds/bnc881578-500.pdf.

What is SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.