SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL

Catalog number BNC941578-100

Price for BNC941578-100

Size / count 1x 100 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941578-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ADD 1; bHLHd1; Class D basic helix-loop-helix protein 1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1c; SREBP-1; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1; Sterol regulatory element binding transcription factor 1; Sterol regulatory element-binding transcription factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SREBF1
Gene ID: 6720
NCBI Gene ID: 592123
UniProt: P36956
Swiss Prot: P36956
Host: Mouse
Species Reactivity: Human
Reactivity: SREBP1
Immunogen: Recombinant full-length human SREBF1 protein
Target Antigen: SREBP1
Clonality: Monoclonal
Clone: SREBP1/1578
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Ubiqutious expression in adult and fetal tissues.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 68/125 kDa mature/precursor
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL?

The catalog number for SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL is BNC941578-100.

What sizes are available for SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL in stock?

SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL?

The safety data sheet for SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is SREBP1 (SREBP1/1578), CF594 conjugate, 0.1mg/mL used for?

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.