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Product details

SREBP1 (SREBP1/1578), 0.2mg/mL

Catalog number BNUB1578-500

Price for BNUB1578-500

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Size / count 1x 500 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1578-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ADD 1; bHLHd1; Class D basic helix-loop-helix protein 1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1c; SREBP-1; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1; Sterol regulatory element binding transcription factor 1; Sterol regulatory element-binding transcription factor 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SREBF1
Gene ID
6720
NCBI Gene ID
592123
UniProt
P36956
Swiss Prot
P36956
Host
Mouse
Species Reactivity
Human
Reactivity
SREBP1
Immunogen
Recombinant full-length human SREBF1 protein
Target Antigen
SREBP1
Clonality
Monoclonal
Clone
SREBP1/1578
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Ubiqutious expression in adult and fetal tissues.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
68/125 kDa mature/precursor
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for SREBP1 (SREBP1/1578), 0.2mg/mL?

The catalog number for SREBP1 (SREBP1/1578), 0.2mg/mL is BNUB1578-500.

What sizes are available for SREBP1 (SREBP1/1578), 0.2mg/mL?

SREBP1 (SREBP1/1578), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is SREBP1 (SREBP1/1578), 0.2mg/mL in stock?

SREBP1 (SREBP1/1578), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP1 (SREBP1/1578), 0.2mg/mL?

SREBP1 (SREBP1/1578), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP1 (SREBP1/1578), 0.2mg/mL?

Estimated delivery time for SREBP1 (SREBP1/1578), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP1 (SREBP1/1578), 0.2mg/mL?

The safety data sheet for SREBP1 (SREBP1/1578), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is SREBP1 (SREBP1/1578), 0.2mg/mL used for?

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol reg

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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