SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL

Catalog number BNC401579-500

Price for BNC401579-500

Size / count 1x 500 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC401579-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AI608257; bHLHd2; Class D basic helix-loop-helix protein 2; OTTHUMP00000028740; Processed sterol regulatory element-binding protein 2; SRBP2_HUMAN; SREBF 2; Srebf2; SREBF2 protein; SREBP 2; SREBP2; SREBP2gc; sterol regulatory element binding factor 2; Sterol regulatory element binding transcription factor 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SREBF2
Gene ID: 6721
NCBI Gene ID: 443258
UniProt: Q12772
Swiss Prot: Q12772
Host: Mouse
Species Reactivity: Human
Reactivity: SREBP2
Immunogen: Recombinant full-length human SREBF2 protein
Target Antigen: SREBP2
Clonality: Monoclonal
Clone: SREBP2/1579
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Ubiqutious expression in adult and fetal tissues. Hep2 or HeLa cells.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 68/125 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL?

The catalog number for SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL is BNC401579-500.

What sizes are available for SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL?

SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL in stock?

SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL?

SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL?

The safety data sheet for SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is SREBP2 (SREBP2/1579), CF640R conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.