SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL

Catalog number BNC471579-500

Price for BNC471579-500

Size / count 1x 500 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471579-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AI608257; bHLHd2; Class D basic helix-loop-helix protein 2; OTTHUMP00000028740; Processed sterol regulatory element-binding protein 2; SRBP2_HUMAN; SREBF 2; Srebf2; SREBF2 protein; SREBP 2; SREBP2; SREBP2gc; sterol regulatory element binding factor 2; Sterol regulatory element binding transcription factor 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SREBF2
Gene ID: 6721
NCBI Gene ID: 443258
UniProt: Q12772
Swiss Prot: Q12772
Host: Mouse
Species Reactivity: Human
Reactivity: SREBP2
Immunogen: Recombinant full-length human SREBF2 protein
Target Antigen: SREBP2
Clonality: Monoclonal
Clone: SREBP2/1579
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Ubiqutious expression in adult and fetal tissues. Hep2 or HeLa cells.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 68/125 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL?

The catalog number for SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL is BNC471579-500.

What sizes are available for SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL?

SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL in stock?

SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL?

SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL?

The safety data sheet for SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c04b/msds/bnc471579-500.pdf.

What is SREBP2 (SREBP2/1579), CF647 conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.