Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL — image 1 of 2

Product details

Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL

Catalog number BNC041621-500

Price for BNC041621-500

Size / count 1x 500 µL

About this product

CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for prostate adenocarcinoma, and cancers of the lung, stomach, breast, and brain. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041621-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD105; END; Endoglin; Eng; HHT1; S-endoglin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ENG
Gene ID: 2022
NCBI Gene ID: 76753
UniProt: P17813
Swiss Prot: P17813
Host: Mouse
Species Reactivity: Horse, Human, Monkey, Pig, Rat
Reactivity: CD105|Endoglin
Immunogen: Recombinant extracellular fragment of human Endoglin protein (exact sequence is proprietary)
Target Antigen: CD105 | Endoglin
Clonality: Monoclonal
Clone: ENG/1621
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified)
Field of Research: Cancer
Positive Control: HeLa, A431 and HL-60 cells. Colon.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 84 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL?

The catalog number for Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL is BNC041621-500.

What sizes are available for Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL?

Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL in stock?

Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL?

Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Endoglin / CD105 (ENG/1621), CF405S conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.