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Product details
Catalog number BNC681621-100
Price for BNC681621-100
Size / count 1x 100 µL
CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for prostate adenocarcinoma, and cancers of the lung, stomach, breast, and brain. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is BNC681621-100.
Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02af061270361e109128/msds/bnc681621-100.pdf.
CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system a
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.
