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Product details
Catalog number BNC681621-500
Price for BNC681621-500
Size / count 1x 500 µL
CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for prostate adenocarcinoma, and cancers of the lung, stomach, breast, and brain. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is BNC681621-500.
Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Endoglin / CD105 (ENG/1621), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106b62/msds/bnc681621-500.pdf.
CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system a
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
