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Product details

CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1629-500

Price for BNCB1629-500

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Size / count 1x 500 µL

About this product

This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1629-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
LHR; BA-1; chondroitin sulfate proteoglycan 8 (CSPG8) ; Epican; Extracellular Matrix Receptor III (ECM III) ; GP90 Lymphocyte Homing Adhesion Receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan Sulfate Proteoglycan; Hermes Antigen; HAS; HUTCH I; Hyaluronate Receptor; Indian blood group; Inlu Related p80 Glycoprotein; Ly 24; MDU2; MDU3; MIC4; MUTCH I; Phagocytic Glycoprotein 1 (PGP-1)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD44
Gene ID
960
NCBI Gene ID
502328
UniProt
P16070
Swiss Prot
P16070
Host
Mouse
Species Reactivity
Human
Reactivity
CD44v6
Immunogen
Recombinant human CD44v3-10 Protein
Target Antigen
CD44v6
Clonality
Monoclonal
Clone
2F10
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IF (published) |IHC, FFPE (published) |IP (published) |WB (published)
Positive Control
Cervix or Tongue Squamous Cell Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
80-95 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Arthritis Rheumatism (2002) 46(8): 2059-2064. (IF; IP; WB; functional studies) J Inv Dermatol (2010) 130(7):1893-1903. (functional studies) Cancer Sci (2015) 106: 1421-1428. (IHC, FFPE; Flow)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL?

The catalog number for CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL is BNCB1629-500.

What sizes are available for CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL?

CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL in stock?

CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL?

CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD44v6 (Marker of Tumor Metastasis) (2F10), Biotin conjugate, 0.1mg/mL used for?

This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exon

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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