TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL

Catalog number BNC401648-100

Price for BNC401648-100

Size / count 1x 100 µL

About this product

TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity) . PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC401648-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Collagenase inhibitor; EPO; Erythroid-Potentiating Activity (EPA) ; Fibroblast collagenase inhibitor; Human Collagenase Inhibitor (HCI) ; Metalloproteinase inhibitor 1; Tissue Inhibitor of Metalloproteinase 1 (TIMP1)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TIMP1
Gene ID: 7076
NCBI Gene ID: 522632
UniProt: P01033
Swiss Prot: P01033
Host: Mouse
Species Reactivity: Human
Reactivity: TIMP1
Immunogen: A synthetic peptide (aa 72-82) of human TIMP1 protein (FQALGDAADIR)
Target Antigen: TIMP1
Clonality: Monoclonal
Clone: 2A5
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (published) |WB (published)
Positive Control: 293 cells. Colon Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 23 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Gut (1998) 43:791-797. (WB; IHC, FFPE)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL?

The catalog number for TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL is BNC401648-100.

What sizes are available for TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL?

TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL in stock?

TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL?

TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL?

The safety data sheet for TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF640R conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.