CD36 (Platelet & Microvessel Marker) (GPIIIb/1654), CF647 conjugate, 0.1mg/mL

About this product

Recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN) . CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC471654-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Adipocyte membrane protein; CHDS7; Collagen receptor; platelet; fatty acid translocase (FAT) ; Fatty acid transport protein; glycoprotein iiib (GP IIIb) ; PAS IV; PAS-4; pas4 protein; platelet collagen receptor; Platelet glycoprotein 4; scarb3; Scavenger receptor class B member 3; thrombospondin receptor

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CD36

Gene ID

948

NCBI Gene ID

120949

UniProt

P16671

Swiss Prot

P16671

Host

Mouse

Species Reactivity

Human

Reactivity

CD36

Immunogen

Recombinant human GPIIIb protein

Target Antigen

CD36

Clonality

Monoclonal

Clone

GPIIIb/1654

Type

Primary

Source

Animal

Origin

Animal

Positive Control

HEL or U937 cells. Platelets, monocytes, macrophages, microvascular endothelial cells in a tonsil.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

80-90 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2a, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF647