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Product details
Catalog number BNC471656-500
Price for BNC471656-500
Size / count 1x 500 µL
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF647 conjugate, 0.1mg/mL is BNC471656-500.
HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02af061270361e10921b/msds/bnc471656-500.pdf.
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
