HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL

Catalog number BNC881656-500

Price for BNC881656-500

Size / count 1x 500 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881656-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: HLA-DP; HLA-DQ; HLA-DR
Gene ID: 3115; 3117; 3122
NCBI Gene ID: 347270; 550475; 520048
UniProt: P04440; P01908; P01909; P01920; P01903
Swiss Prot: P04440; P01908; P01909; P01920; P01903
Host: Mouse
Species Reactivity: Human
Reactivity: HLA-DP/-DQ/-DR
Immunogen: Cells from human tonsil
Target Antigen: HLA-DP/-DQ/-DR
Clonality: Monoclonal
Clone: CR3/43
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: Ramos, Raji cells. Tonsil, Spleen or lymph node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 36 kDa (? chain) and 27 kDa (? chain)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL?

The catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL is BNC881656-500.

What sizes are available for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL in stock?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL?

The safety data sheet for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF488A conjugate, 0.1mg/mL used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.