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Product details

HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL

Catalog number BNC941656-100

Price for BNC941656-100

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Size / count 1x 100 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941656-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DP; HLA-DQ; HLA-DR
Gene ID
3115; 3117; 3122
NCBI Gene ID
347270; 550475; 520048
UniProt
P04440; P01908; P01909; P01920; P01903
Swiss Prot
P04440; P01908; P01909; P01920; P01903
Host
Mouse
Species Reactivity
Human
Reactivity
HLA-DP/-DQ/-DR
Immunogen
Cells from human tonsil
Target Antigen
HLA-DP/-DQ/-DR
Clonality
Monoclonal
Clone
CR3/43
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
Ramos, Raji cells. Tonsil, Spleen or lymph node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
36 kDa (? chain) and 27 kDa (? chain)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL?

The catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL is BNC941656-100.

What sizes are available for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL in stock?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL?

The safety data sheet for HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HLA-DP/-DQ/-DR (MHC II) (CR3/43), CF594 conjugate, 0.1mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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