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Product details

HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL

Catalog number BNUM1656-50

Price for BNUM1656-50

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Size / count 1x 50 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM1656-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DP; HLA-DQ; HLA-DR
Gene ID
3115; 3117; 3122
NCBI Gene ID
347270; 550475; 520048
UniProt
P04440; P01908; P01909; P01920; P01903
Swiss Prot
P04440; P01908; P01909; P01920; P01903
Host
Mouse
Species Reactivity
Human
Reactivity
HLA-DP/-DQ/-DR
Immunogen
Cells from human tonsil
Target Antigen
HLA-DP/-DQ/-DR
Clonality
Monoclonal
Clone
CR3/43
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
Ramos, Raji cells. Tonsil, Spleen or lymph node.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
36 kDa (? chain) and 27 kDa (? chain)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL?

The catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is BNUM1656-50.

What sizes are available for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is available in the following size(s): 1x 50 µL.

Is HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL in stock?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL?

HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL?

Estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL?

The safety data sheet for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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