Product details
Catalog number BNUM1656-50
Price for BNUM1656-50
Size / count 1x 50 µL
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is BNUM1656-50.
HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is available in the following size(s): 1x 50 µL.
HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is manufactured by Biotium.
Estimated delivery time for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for HLA-DP/-DQ/-DR (MHC II) (CR3/43), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.