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Product details

CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL

Catalog number BNUB1657-100

Price for BNUB1657-100

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Size / count 1x 100 µL

About this product

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1657-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cortical thymocyte antigen CD1A; Epidermal dendritic cell marker CD1a; FCB6; HTA1; T cell surface antigen T6 / Leu 6; T-Cell Surface Glycoprotein CD1A
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD1A
Gene ID
909
NCBI Gene ID
1309
UniProt
P06126
Swiss Prot
P06126
Host
Rabbit
Species Reactivity
Human
Reactivity
CD1a|HTA1
Immunogen
Recombinant human CD1a protein
Target Antigen
CD1a | HTA1
Clonality
Polyclonal
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
49 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL?

The catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL is BNUB1657-100.

What sizes are available for CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL in stock?

CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL?

Estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL?

The safety data sheet for CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD1a / HTA1 (Mature Langerhans Cells Marker), 0.2mg/mL used for?

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein,

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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