Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL

Catalog number BNC471661-100

Price for BNC471661-100

Size / count 1x 100 µL

About this product

The insulin receptor (INSR) is a heterodimeric protein complex that has an intracellular subunit, which is disulfide-linked to a transmembrane segment. The insulin ligand binds to the INSR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to INSR induces phosphorylation of intra-cellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. Type 1 diabetes is an autoimmune condition of the endocrine pancreas that results in destruction of insulin secreting cells and a progressive loss in insulin-sensitive glucose uptake by cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471661-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD220; HHF5; HINSR A; INSR; Insulin receptor; Insulin receptor subunit alpha; INSR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: INSR
Gene ID: 3643
NCBI Gene ID: 465744
UniProt: P06213
Swiss Prot: P06213
Host: Mouse
Species Reactivity: Human
Reactivity: Insulin Receptor Alpha
Immunogen: Recombinant fragment of extracellular domain of human Insulin Receptor alpha (exact sequence is proprietary)
Target Antigen: Insulin Receptor Alpha
Clonality: Monoclonal
Clone: INSR/1661
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Jurkat cells. Human pancreas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 135 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL?

The catalog number for Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL is BNC471661-100.

What sizes are available for Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL?

Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL in stock?

Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL?

Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b0061270361e1097b2/msds/bnc471661-100.pdf.

What is Insulin Receptor Alpha (INSR/1661), CF647 conjugate, 0.1mg/mL used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.