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Product details

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL

Catalog number BNC881671-100

Price for BNC881671-100

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Size / count 1x 100 µL

About this product

Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL) . Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881671-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Annexin-1; Calpactin-2; Chromobindin-9; Phospholipase A2 inhibitory protein; LPC1; p35
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ANXA1
Gene ID
301
NCBI Gene ID
494173
UniProt
P04083
Swiss Prot
P04083
Host
Mouse
Species Reactivity
Human
Reactivity
Annexin A1
Immunogen
Recombinant full-length human Annexin A1 protein
Target Antigen
Annexin A1
Clonality
Monoclonal
Clone
ANXA1/1671
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
A431 and K562 cell lysates. Human esophagus, placenta and prostate tissues.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL?

The catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL is BNC881671-100.

What sizes are available for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL in stock?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), CF488A conjugate, 0.1mg/mL used for?

Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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