Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL

Catalog number BNUM1671-50

Price for BNUM1671-50

Size / count 1x 50 µL

About this product

Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL) . Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM1671-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Annexin-1; Calpactin-2; Chromobindin-9; Phospholipase A2 inhibitory protein; LPC1; p35
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ANXA1
Gene ID: 301
NCBI Gene ID: 494173
UniProt: P04083
Swiss Prot: P04083
Host: Mouse
Species Reactivity: Human
Reactivity: Annexin A1
Immunogen: Recombinant full-length human Annexin A1 protein
Target Antigen: Annexin A1
Clonality: Monoclonal
Clone: ANXA1/1671
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: A431 and K562 cell lysates. Human esophagus, placenta and prostate tissues.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL?

The catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL is BNUM1671-50.

What sizes are available for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL in stock?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL?

Estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL?

The safety data sheet for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1671), 1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.