Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL

Catalog number BNC041672-500

Price for BNC041672-500

Size / count 1x 500 µL

About this product

Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL) . Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041672-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Annexin-1; Calpactin-2; Chromobindin-9; Phospholipase A2 inhibitory protein; LPC1; p35
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ANXA1
Gene ID: 301
NCBI Gene ID: 494173
UniProt: P04083
Swiss Prot: P04083
Host: Mouse
Species Reactivity: Human
Reactivity: Annexin A1
Immunogen: Recombinant full-length human Annexin A1 protein
Target Antigen: Annexin A1
Clonality: Monoclonal
Clone: ANXA1/1672
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |WB (verified)
Positive Control: HeLa. A431 and K562 cells; human esophagus, placenta and prostate tissues.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL?

The catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL is BNC041672-500.

What sizes are available for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL in stock?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Annexin A1 / (Hairy Cell Leukemia Marker) (ANXA1/1672), CF405S conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.