TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL

Catalog number BNC881674-100

Price for BNC881674-100

Size / count 1x 100 µL

About this product

This antibody recognizes a human 17-26 kDa protein, which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha) . TNF-alpha can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881674-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: APC1; Cachectin; Differentiation inducing factor (DIF) ; Macrophage cytotoxic factor (MCF) ; Necrosin; TNF alpha; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TNF
Gene ID: 7124
NCBI Gene ID: 241570
UniProt: P01375
Swiss Prot: P01375
Host: Rabbit
Species Reactivity: Human, Rat
Reactivity: TNF-Alpha
Immunogen: Recombinant full-length human TNF-alpha protein
Target Antigen: TNF-Alpha
Clonality: Polyclonal
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HeLa, HL-60, or A431 cells. Pancreas or Histiocytoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 17 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL?

The catalog number for TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL is BNC881674-100.

What sizes are available for TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL?

TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL in stock?

TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL?

TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL?

The safety data sheet for TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TNF-alpha (Tumor Necrosis Factor alpha), CF488A conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.