TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1674-500

Price for BNCB1674-500

Size / count 1x 500 µL

About this product

This antibody recognizes a human 17-26 kDa protein, which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha) . TNF-alpha can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1674-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: APC1; Cachectin; Differentiation inducing factor (DIF) ; Macrophage cytotoxic factor (MCF) ; Necrosin; TNF alpha; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TNF
Gene ID: 7124
NCBI Gene ID: 241570
UniProt: P01375
Swiss Prot: P01375
Host: Rabbit
Species Reactivity: Human, Rat
Reactivity: TNF-Alpha
Immunogen: Recombinant full-length human TNF-alpha protein
Target Antigen: TNF-Alpha
Clonality: Polyclonal
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HeLa, HL-60, or A431 cells. Pancreas or Histiocytoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 17 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL?

The catalog number for TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL is BNCB1674-500.

What sizes are available for TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL?

TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL in stock?

TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL?

TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL?

The safety data sheet for TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100df0/msds/bncb1674-500.pdf.

What is TNF-alpha (Tumor Necrosis Factor alpha), Biotin conjugate, 0.1mg/mL used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.