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Product details

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL

Catalog number BNC941675-100

Price for BNC941675-100

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Size / count 1x 100 µL

About this product

Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941675-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Caldesmon; Caldesmon 1; Caldesmon 1 Isoform 1; CDM; HCAD
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CALD1
Gene ID
800
NCBI Gene ID
490203
UniProt
Q05682
Swiss Prot
Q05682
Host
Rabbit
Species Reactivity
Human, Rat
Reactivity
Caldesmon, HMW
Immunogen
Recombinant human CALD1 protein fragment
Target Antigen
Caldesmon, HMW
Clonality
Polyclonal
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cytoskeleton
Positive Control
Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
150 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL?

The catalog number for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL is BNC941675-100.

What sizes are available for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL in stock?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), CF594 conjugate, 0.1mg/mL used for?

Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150 kDa) is predominantly expressed in smooth muscle whe

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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