Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1675-100

Price for BNCB1675-100

Size / count 1x 100 µL

About this product

Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1675-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Caldesmon; Caldesmon 1; Caldesmon 1 Isoform 1; CDM; HCAD
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CALD1
Gene ID: 800
NCBI Gene ID: 490203
UniProt: Q05682
Swiss Prot: Q05682
Host: Rabbit
Species Reactivity: Human, Rat
Reactivity: Caldesmon, HMW
Immunogen: Recombinant human CALD1 protein fragment
Target Antigen: Caldesmon, HMW
Clonality: Polyclonal
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cytoskeleton
Positive Control: Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 150 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL?

The catalog number for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL is BNCB1675-100.

What sizes are available for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL in stock?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker), Biotin conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.