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Product details

CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL

Catalog number BNC941680-500

Price for BNC941680-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45) . Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4 T-cells, 50% of peripheral CD8 T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4 or CD8 T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO ve) from B cell lymphomas (CD45RA ve) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941680-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B220; CD45R; GP180; Leukocyte common antigen (LCA) ; Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC) ; Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PTPRC
Gene ID
5788
NCBI Gene ID
654514
UniProt
P08575
Swiss Prot
P08575
Host
Mouse
Species Reactivity
Human
Reactivity
CD45RA
Immunogen
Stimulated human leukocytes
Target Antigen
CD45RA
Clonality
Monoclonal
Clone
K4B5
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Immunology, Signal transduction
Positive Control
Daudi, Raji, IM9 and human lymphocytes. Human spleen, lymph nodes and tonsils.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
205-220 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL?

The catalog number for CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL is BNC941680-500.

What sizes are available for CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL?

CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL in stock?

CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL?

CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL?

The safety data sheet for CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD45RA (Leukocyte Marker) (K4B5), CF594 conjugate, 0.1mg/mL used for?

Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45) . Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms,

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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