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Product details

Calponin-1 (Smooth Muscle Marker), 1mg/mL

Catalog number BNUM1685-50

Price for BNUM1685-50

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Size / count 1x 50 µL

About this product

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM1685-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Calponin-1; CNN1; Calponin 1 basic smooth muscle; Calponin H1 smooth muscle
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CNN1
Gene ID
1264
NCBI Gene ID
465929
UniProt
P51911
Swiss Prot
P51911
Host
Rabbit
Species Reactivity
Human, Rat
Reactivity
Calponin-1
Immunogen
Recombinant human CNN1 protein
Target Antigen
Calponin-1
Clonality
Polyclonal
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cytoskeleton
Positive Control
Myoepithelial cells in breast ducts
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
34 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Calponin-1 (Smooth Muscle Marker), 1mg/mL?

The catalog number for Calponin-1 (Smooth Muscle Marker), 1mg/mL is BNUM1685-50.

What sizes are available for Calponin-1 (Smooth Muscle Marker), 1mg/mL?

Calponin-1 (Smooth Muscle Marker), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Calponin-1 (Smooth Muscle Marker), 1mg/mL in stock?

Calponin-1 (Smooth Muscle Marker), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calponin-1 (Smooth Muscle Marker), 1mg/mL?

Calponin-1 (Smooth Muscle Marker), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Calponin-1 (Smooth Muscle Marker), 1mg/mL?

Estimated delivery time for Calponin-1 (Smooth Muscle Marker), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Calponin-1 (Smooth Muscle Marker), 1mg/mL?

The safety data sheet for Calponin-1 (Smooth Muscle Marker), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Calponin-1 (Smooth Muscle Marker), 1mg/mL used for?

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing sm

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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