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Product details
Catalog number BNUB1696-100
Price for BNUB1696-100
Size / count 1x 100 µL
CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. The novel finding that CTLA-4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for CTLA4 / CD152 (Negative Regulator of T-Cells) (L4P2F5.F10), 0.2mg/mL is BNUB1696-100.
CTLA4 / CD152 (Negative Regulator of T-Cells) (L4P2F5.F10), 0.2mg/mL is available in the following size(s): 1x 100 µL.
CTLA4 / CD152 (Negative Regulator of T-Cells) (L4P2F5.F10), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
CTLA4 / CD152 (Negative Regulator of T-Cells) (L4P2F5.F10), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for CTLA4 / CD152 (Negative Regulator of T-Cells) (L4P2F5.F10), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for CTLA4 / CD152 (Negative Regulator of T-Cells) (L4P2F5.F10), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e10238e/msds/bnub1696-100.pdf.
CTLA4 (CD152) is a cell surface receptor that behaves as a negative regulator of the proliferation and the effector function of T cells. It contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been character
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
