PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL

Catalog number BNC041703-100

Price for BNC041703-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041703-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Paired box 8; Paired box gene 8; paired box homeotic gene 8; Paired box protein Pax-8; Paired domain gene 8; PAX8
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PAX8
Gene ID: 7849
NCBI Gene ID: 469728
UniProt: Q06710
Swiss Prot: Q06710
Host: Mouse
Species Reactivity: Human
Reactivity: PAX8
Immunogen: Recombinant human PAX8 protein
Target Antigen: PAX8
Clonality: Monoclonal
Clone: PAX8/1491 PAX8/1492
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: Raji cells. Renal Cell Carcinoma (RCC)
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 62 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL?

The catalog number for PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL is BNC041703-100.

What sizes are available for PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL?

PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL in stock?

PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL?

PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL?

The safety data sheet for PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PAX8 (Renal Cell Marker) (PAX8/1491 + PAX8/1492), CF405S conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.