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Product details

MDM2 (SMP14), CF594 conjugate, 0.1mg/mL

Catalog number BNC941721-100

Price for BNC941721-100

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Size / count 1x 100 µL

About this product

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941721-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ACTFS; Double minute 2 protein; E3 ubiquitin-protein ligase; Hdm2; HDMX; MDM2; MDM2 oncogene E3 ubiquitin protein ligase; MDM2BP; Mouse Double Minute 2; MTBP; Murine Double Minute Chromosome 2; p53 Binding Protein Mdm2; p53-binding protein Mdm2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MDM2
Gene ID
4193
NCBI Gene ID
484551
UniProt
Q00987
Swiss Prot
Q00987
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
MDM2
Immunogen
A synthetic peptide (aa 154-167) of human MDM2 protein.
Target Antigen
MDM2
Clonality
Monoclonal
Clone
SMP14
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
HepG2 cells. Breast Carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
90 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for MDM2 (SMP14), CF594 conjugate, 0.1mg/mL?

The catalog number for MDM2 (SMP14), CF594 conjugate, 0.1mg/mL is BNC941721-100.

What sizes are available for MDM2 (SMP14), CF594 conjugate, 0.1mg/mL?

MDM2 (SMP14), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MDM2 (SMP14), CF594 conjugate, 0.1mg/mL in stock?

MDM2 (SMP14), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MDM2 (SMP14), CF594 conjugate, 0.1mg/mL?

MDM2 (SMP14), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MDM2 (SMP14), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MDM2 (SMP14), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MDM2 (SMP14), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MDM2 (SMP14), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100a9d/msds/bnc941721-100.pdf.

What is MDM2 (SMP14), CF594 conjugate, 0.1mg/mL used for?

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishin

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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