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Product details

Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL

Catalog number BNC051722-500

Price for BNC051722-500

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Size / count 1x 500 µL

About this product

Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC051722-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CMD1I; CSM1; CSM2; DES; Intermediate filament protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DES
Gene ID
1674
NCBI Gene ID
594952
UniProt
P17661
Swiss Prot
P17661
Host
Mouse
Species Reactivity
Chicken, Hamster, Human, Rat
Reactivity
Desmin
Immunogen
Proteins from human Leiomyoma
Target Antigen
Desmin
Clonality
Monoclonal
Clone
D33
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
SJRH30 Cells. Uterus or Leiomyosarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405M

Frequently Asked Questions

What is the catalog number for Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL?

The catalog number for Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL is BNC051722-500.

What sizes are available for Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL in stock?

Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL?

Estimated delivery time for Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL?

The safety data sheet for Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Desmin (Muscle Cell Marker) (D33), CF405M conjugate, 0.1mg/mL used for?

Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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