MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL

Catalog number BNC471729-500

Price for BNC471729-500

Size / count 1x 500 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471729-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MMP3; Proteoglycanase; SL1; STMY1; STR1; Stromelysin-1; Transin 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MMP3
Gene ID: 4314
NCBI Gene ID: 375129
UniProt: P08254
Swiss Prot: P08254
Host: Mouse
Species Reactivity: Human
Reactivity: MMP3
Immunogen: Recombinant fragment corresponding to amino acids 317-327 of human MMP3.
Target Antigen: MMP3
Clonality: Monoclonal
Clone: 1B4
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (published) |WB (published)
Positive Control: A431 cells. Prostate or Lung Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 57 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Clin Cancer Res (2006) 12(4) 1184-1191. (IHC, FFPE) Placenta (2010) 31(10): 886-892. (WB)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL?

The catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL is BNC471729-500.

What sizes are available for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL in stock?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a6061270361e105cf3/msds/bnc471729-500.pdf.

What is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), CF647 conjugate, 0.1mg/mL used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.